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- Nitrates -


General Information:

Names:
Wikipedia entry:
Dr. Ray Shahelien entry: 

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Observations:


Nitrates

See also Peroxynitrates

A Revolutionary Breakthrough in Alzheimer's Disease
(Nitrates and nitrites in foods may cause AD - Dr. Oz Show)
April 13, 2011

On April 7, 2011, a former surgeon general and Dr. Suzanne de la Monte appeared on the Dr. Oz Show entitled, "A Revolutionary Breakthrough in Alzheimer's Disease," (can be watched on his website) where she presented her important research. She is the doctor who coined the term "type 3 diabetes" in reference to Alzheimer's disease.She found by accident that giving a nitrosamine compound called streptozotocin, used to deliberately produce diabetes, caused Alzheimer's in her lab mice. She learned that the brain produces its own insulin. She further found that this compound causes production of toxic lipids in the liver that cross the blood brain barrier and damage certain cells such that the brain develops insulin deficiency and insulin resistance. Nitrites and nitrates, found in very many processed foods, are nitrosamine compounds and could very well explain the epidemics of Alzheimer's, autism, diabetes, MS, Parkinson's and ALS, along with other neurodegenerative diseases that have insulin resistance, decreased glucose uptake as part of the process. These diseases have all been on the increase as processed foods have taken over our diets. I will add Dr. de la Monte's references to the website http://www.coconutketones.com, in the very near future.

These nitrites and nitrates are in most bacon, ham and other meats, deli meats, whether pre-packaged or cut at the counter, processed cheeses, cereals, breads, pretzels, crackers, white flour and anything that contains white flour, certain beers, scotch and some other whiskeys. Something that has caught my attention for newborns and children: I found one of these offending compounds, thiamine mononitrate, in the Carnation infant formulas, some of the jarred baby foods, especially the junior combinations, cereals and other infant prepared foods such as macaroni and cheese...
http://alzheimers.infopop.cc/eve/forums/a/tpc/f/762104261/m/8724020397

   
Dietary vitamin E and selenium and toxicity of nitrite and nitrate

Toxicology. 2002 Nov 15;180(2):195-207.
Chow CK, Hong CB.
Graduate Center for Nutritional Sciences, University of Kentucky, Lexington, KY

Abstract

Nitrites and nitrates are important antimicrobial and flavoring/coloring agents in meat and fish products. However, nitrites and nitrates may cause methemoglobinemia and other illness, and may react with certain amines to form carcinogenic nitrosamines.

The nutritional status of vitamin E and selenium has long been associated with nitrite and nitrate toxicity, although the mechanism involved is not yet clear.

Information available recently shows that nitrites and nitrates are both oxidation products and ready sources of nitric oxide (NO√), that NO√ reacts rapidly with superoxide to form highly reactive peroxynitrite (ONOO−), and that vitamin E may mediate the generation and availability of superoxide and NO√.

Increased formation of ONOO− resulting from nitrite treatment and low intake of vitamin E and selenium may thus be the critical event leading to tissue damage and animal mortality observed previously.

The protection against the adverse effects of nitrites/nitrates by vitamin E is attributed to its ability to reduce ONOO− formation, while selenium exerts its protective effects via seleno-enzymes/compounds, which reduce ONOO− formed.

http://www.ncbi.nlm.nih.gov/pubmed/12324194

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Updated: July 2, 2012
Inception: July 2, 2012