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Glymphatic System -


General Information:

Names:
Wikipedia entry:
Dr. Ray Shahelien entry: 

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Observations:


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Known sources:

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Natural sources:


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References:

[ Glymphatic System, Amyloid Beta (Amyloid β), Brain Injury]

[Could certain drugs, like the Russian antihistamine Dimebon, actually have an effect by enhancing the “Glymphatic System”?]

Previously Unknown Cleaning System in Brain: Newer Imaging Technique Brings 'Glymphatic System' to Light
ScienceDaily (Aug. 15, 2012) — A previously unrecognized system that drains waste from the brain at a rapid clip has been discovered by neuroscientists at the University of Rochester Medical Center. The findings were published online August 15 in Science Translational Medicine… "If the glymphatic system fails to cleanse the brain as it is meant to, either as a consequence of normal aging, or in response to brain injury, waste may begin to accumulate in the brain. This may be what is happening with amyloid deposits in Alzheimer's disease," said Iliff. "Perhaps increasing the activity of the glymphatic system might help prevent amyloid deposition from building up or could offer a new way to clean out buildups of the material in established Alzheimer's disease," he added…
http://www.sciencedaily.com/releases/2012/08/120815142042.htm

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β.
Jeffrey J. Iliff, Minghuan Wang, Yonghong Liao, Benjamin A. Plogg, Weiguo Peng, Georg A. Gundersen, Helene Benveniste, G. Edward Vates, Rashid Deane, Steven A. Goldman, Erlend A. Nagelhus, and Maiken Nedergaard.
Science Translational Medicine, 2012; DOI: 10.1126/scitranslmed.3003748
http://stm.sciencemag.org/content/4/147/147ra111

[NEED PUBMED CITATION]



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Updated: July 25, 2012
Inception: July 25, 2012