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- Chitosan (water-soluble, Chitosan oligosaccharide) -
General Information:
Names:
Wikipedia entry:
Dr. Ray Shahelien entry:
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Observations:
Here is a Pubmed citation:
It says that that WSC (water-soluble chitosan) inhibited
"TNF-alpha". I assume there is a "TNF-beta", etc. What brand of
TNF does etanercept inhibit?
Interestingly, they used desferrioxamine (desferral) to create the
elevated levels of TNF. But, other researchers in Canada have used
desferral to arrest the progression of AD. So, *there's* a
puzzle...
Desferral is used primarily as a powerful iron chelator, on the
same order as phytic acid (IP6).
This research was done in Japan. I wonder if WSC is available in
the US?
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0G-451DD9T-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ee4019d7850933a86133b8fc20be802d
From the Alz.org message board "Medications/Treatments for
Alzheimer's and Other Related Dementias":
Posted July 23, 2008 01:43 PM
After
very extensive review of nearly everything out there for
treatment of AD, I have come to the conclusion that
water-soluble chitosan (WSC) is the only non-drug "supplement"
out there that targets TNF. Let me say that again...WSC targets
TNF in the brain. Because it appears to be safe, has never been
linked to shell-fish allergies (a topic addressed in the
chitosan literature) is marketed in edible form, and is used as
a general energy and anti-aging tonic, mostly in China, and has
animal model AD research showing that it targets TNF in a manner
similar to Enbrel, I think it is worthy of trying...
http://alzheimers.infopop.cc/eve/forums/a/tpc/f/762104261/m/4081064272?r=2661005413#2661005413
Sources???: http://en.haidebei.com/newEbiz1/EbizPortalFG/portal/html/ProductInfoExhibit.html?ProductInfoExhibit_ProductID=c373e911f56523978f6e9d2e0a9b4fa4&ProductInfoExhibit_isRefreshParent=false
http://www.outletnutrition.com/713947559905.html
http://heavenshealth.com/benefits.htm
This is a US supplier of water soluble chitosan.
http://www.alibaba.com/countrysearch/US-suppliers/Water_Soluble_Chitosan.html
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Known sources:
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Natural sources:
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References:
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Updated: July 2, 2012
Inception: July 2, 2012