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- Nitrates -
General Information:
Names:
Wikipedia entry:
Dr. Ray Shahelien entry:
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Observations:
Nitrates
See also Peroxynitrates
A
Revolutionary Breakthrough in Alzheimer's Disease
(Nitrates and nitrites in foods
may cause AD - Dr. Oz Show)
April
13, 2011
On
April 7, 2011, a former surgeon general and Dr. Suzanne de la
Monte appeared on the Dr. Oz Show entitled, "A Revolutionary
Breakthrough in Alzheimer's Disease," (can be watched on his
website) where she presented her important research. She is the
doctor who coined the term "type 3 diabetes" in reference to
Alzheimer's disease.She found by accident that giving a
nitrosamine compound called streptozotocin, used to deliberately
produce diabetes, caused Alzheimer's in her lab mice. She
learned that the brain produces its own insulin. She further
found that this compound causes production of toxic lipids in
the liver that cross the blood brain barrier and damage certain
cells such that the brain develops insulin deficiency and
insulin resistance. Nitrites and nitrates, found in very many
processed foods, are nitrosamine compounds and could very well
explain the epidemics of Alzheimer's, autism, diabetes, MS,
Parkinson's and ALS, along with other neurodegenerative diseases
that have insulin resistance, decreased glucose uptake as part
of the process. These diseases have all been on the increase as
processed foods have taken over our diets. I will add Dr. de la
Monte's references to the website http://www.coconutketones.com,
in the very near future.
These
nitrites and nitrates are in most bacon, ham and other meats,
deli meats, whether pre-packaged or cut at the counter,
processed cheeses, cereals, breads, pretzels, crackers, white
flour and anything that contains white flour, certain beers,
scotch and some other whiskeys. Something that has caught my
attention for newborns and children: I found one of these
offending compounds, thiamine mononitrate, in the Carnation
infant formulas, some of the jarred baby foods, especially the
junior combinations, cereals and other infant prepared foods
such as macaroni and cheese...
http://alzheimers.infopop.cc/eve/forums/a/tpc/f/762104261/m/8724020397
Dietary
vitamin E and selenium and toxicity of nitrite and nitrate
Toxicology.
2002
Nov 15;180(2):195-207.
Chow
CK, Hong CB.
Graduate
Center
for Nutritional Sciences, University of Kentucky, Lexington, KY
Abstract
Nitrites
and nitrates are important antimicrobial and flavoring/coloring
agents in meat and fish products. However, nitrites and nitrates
may cause methemoglobinemia and other illness, and may react
with certain amines to form carcinogenic nitrosamines.
The
nutritional status of vitamin E and selenium has long been
associated with nitrite and nitrate toxicity, although the
mechanism involved is not yet clear.
Information
available
recently shows that nitrites and nitrates are both oxidation
products and ready sources of nitric oxide (NO√), that NO√
reacts rapidly with superoxide to form highly reactive
peroxynitrite (ONOO−), and that vitamin E may mediate the
generation and availability of superoxide and NO√.
Increased
formation
of ONOO− resulting from nitrite treatment and low intake of
vitamin E and selenium may thus be the critical event leading to
tissue damage and animal mortality observed previously.
The
protection against the adverse effects of nitrites/nitrates by
vitamin E is attributed to its ability to reduce ONOO−
formation, while selenium exerts its protective effects via
seleno-enzymes/compounds, which reduce ONOO− formed.
http://www.ncbi.nlm.nih.gov/pubmed/12324194
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Known sources:
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Natural sources:
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References:
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Updated: July 2, 2012
Inception: July 2, 2012